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Embrace the joy of parenting with Best IMSI Treatment In Noida

Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) is an advanced IVF technique that uses high-magnification digital microscopy to select the healthiest sperm for fertilization. This precision-based procedure helps embryologists identify subtle sperm abnormalities before injection into the egg, improving the chances of successful fertilization and healthy embryo development.

Embrace the joy of parenting with IMSI Treatment In Noida.

Intracytoplasmic Morphologically Selected Sperm Injection (IMSI) is an advanced IVF technique that uses high-magnification digital microscopy to select the healthiest sperm for fertilization. This precision-based procedure helps embryologists identify subtle sperm abnormalities before injection into the egg, improving the chances of successful fertilization and healthy embryo development.

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What Is IMSI Treatment?

The IMSI full form is Intracytoplasmic Morphologically Selected Sperm Injection. It is an advanced sperm-selection technique used during ICSI, where sperm are examined under very high magnification before one is selected for injection into an egg.

IMSI allows embryologists to assess sperm morphology in greater detail than conventional ICSI. The aim is to identify sperm with more suitable visible characteristics before fertilisation.

— TREATMENT PROCEDURE

IMSI Treatment Procedure Step by Step

The IMSI procedure is performed as part of an IVF-ICSI cycle. The main difference from conventional ICSI is the use of much higher magnification during sperm selection before fertilisation.

Step 1: Fertility Evaluation & Treatment Planning

Both partners undergo a fertility evaluation before treatment. Semen analysis, reproductive history, previous IVF or ICSI outcomes, ovarian assessment, and other relevant findings help determine whether IMSI should be considered.

Step 2: Egg Retrieval & Semen Preparation

After ovarian stimulation, mature eggs are collected through the IVF process. A fresh or previously frozen semen sample is also prepared in the laboratory to separate suitable motile sperm for further assessment.

Step 3: High-Magnification Sperm Assessment

During IMSI sperm selection, the embryologist examines motile sperm at very high magnification. This provides a more detailed view of sperm shape and visible structures, particularly the sperm head.

Step 4: Sperm Injection Into the Egg

After selecting a suitable sperm, the embryologist uses the ICSI technique to inject it directly into a mature egg. The fertilised eggs are then placed in controlled laboratory conditions.

Step 5: Embryo Development & Transfer

Embryos are monitored as they develop over the following days. Depending on the treatment plan and embryo development, a suitable embryo may be transferred or frozen for use in a later cycle.

What Couples Should Know

Understanding the difference between IMSI and ICSI is important. IMSI offers a more detailed method of looking at sperm, but greater magnification does not automatically mean a better pregnancy or live-birth outcome.

1. IMSI Is an Extension of ICSI

IMSI is not a separate alternative to IVF. It is a sperm-selection method used before ICSI, where the selected sperm is still injected directly into the egg using the standard ICSI procedure.

2. IMSI May Be Considered in Selected Cases

A fertility specialist may discuss IMSI when there are concerns about sperm morphology or previous fertility-treatment outcomes. However, the decision should be based on the couple’s complete clinical and laboratory assessment.

3. Higher Magnification Allows More Detailed Sperm Assessment

IMSI uses magnification of more than 6000× to examine sperm morphology in greater detail, allowing embryologists to look for visible structural features that may not be as easily assessed during conventional ICSI.

4. IMSI Does Not Guarantee Better IVF Success Rates

Current research has not clearly shown that IMSI improves live-birth rates compared with conventional ICSI. Couples should therefore understand why it is being recommended in their specific case before choosing the procedure.

5. IMSI Can Require Additional Laboratory Time

Because sperm are examined individually at very high magnification, the selection process may take longer than conventional ICSI and may involve an additional treatment cost depending on the fertility centre.

Why Choose Zeeva Fertility for IMSI Treatment?

At Zeeva Fertility, advanced laboratory techniques are recommended according to individual fertility needs rather than being added routinely to every IVF cycle.

1. Individualised Fertility Assessment

Each couple is evaluated based on fertility history, sperm parameters, ovarian factors, and previous treatment outcomes before deciding whether conventional IVF, ICSI, IMSI, or another approach may be appropriate.

2. Experienced Embryology Team

IMSI requires careful microscopic assessment and sperm selection. Our embryology team follows structured laboratory protocols while handling sperm, eggs, fertilisation, and embryo development throughout the IVF cycle.

3. Advanced Sperm Selection

High-magnification assessment allows the embryologist to examine sperm morphology in greater detail before selecting a suitable sperm for injection into the egg during the ICSI procedure.

4. Evidence-Based Treatment Planning

Advanced techniques are considered according to individual clinical need. Couples are clearly informed about what IMSI involves, why it may be suggested, and the current evidence regarding its potential benefits.

Meet Our Fertility Experts

The Experts Guiding Your Journey

20+ Years Experience

Dr. Shweta Goswami

Founder & Medical Director, Zeeva Fertility
MBBS (Honours) – Maulana Azad Medical College, New Delhi • MD (Obs & Gyn) – Safdarjung Hospital • FNB in IVF & Reproductive Medicine – IRM Kolkata
20+ Years Experience

Dr. Aarthi Mani

Senior Consultant, Zeeva Fertility
MBBS – Thoothukudi Government Medical College & Hospital (Tamil Nadu Dr. MGR University) • MS (Obstetrics & Gynaecology) – Sri Ramachandra Medical College & Research Institute (Gold Medalist) • FNB (Fellowship in IVF & Reproductive Medicine) – NOVA IVF
16+ years of experience

Dr. Shuchi Lakhanpal Kalia

Senior Fertility Specialist
MBBS - Gold Medalist • MS in Obstetrics and Gynaecology - Delhi University • DNB in Obstetrics and Gynaecology • Diploma in Clinical ART • Fellowship in Minimal Access Surgery.
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10+ Years Experience

Dr. Nidhi Tripathi

Fertility & IVF Specialist
MBBS and MS in Obstetrics & Gynaecology from GSVM Medical College, Kanpur. • Diploma in Clinical ART through the Indian Fertility Society Fellowship Programme, securing 2nd position. • Fellowship in Reproductive Medicine from IIRFT, New Delhi; recognised as the Second Best Clinical IFS Fellow. • Trained in Gynaecological Endoscopy and completed national-level clinical skill development programmes. • Actively participates in academic activities and served as Faculty at AaKRITI – Understanding on Perinatology in 2024.
17+ Years Experience

Dr. Shipra Gupta

IVF & Infertility Specialist
M.B.B.S. VMMC & Safdarjung Hospital, New Delhi (2009) • Diploma (D.G.O.) in Obstetrics and Gynaecology VMMC & Safdarjung( 2011) • M.D. in Obstetrics and Gynaecology VMMC& Safdarjung Hospital, New Delhi (2014) • FOGSI certified Fetal medicine specialist Apollo hospitals( 2014) • Basic and Advanced Laparoscopy at AIIMS, New Delhi (2015) • Fellowship in Pelvic Floor Reconstructive surgeries and Minimal Invasive Gynecology at Scripps Clinic, San Diego, U.S.A (2016) • Fellowship in Reproductive Medicine and ART Max Hospital, New Delhi (2018)
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16+ Years Experience

Dr. Snehal Shah Mahajan

Consultant, Zeeva Fertility
MBBS – ACPM Medical College, Mumbai (2004) • Diploma in Obstetrics & Gynaecology (DGO) – CPS Mumbai (2010) • MBA in Healthcare Management – Sikkim Manipal University (2015) • Certificate Course in Infertility (2021)
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12+ Years Experience

Dr. Mayank Sharma

Associate Consultant, Zeeva Fertility
MBBS – NKPSIMS & Lata Mangeshkar Hospital, Nagpur • DGO – MVJ Medical College & Research Centre, Bengaluru • Fellowship in Reproductive Medicine – IIRFT, New Delhi
7+ Years Experience

Dr. Avnika Kapoor

Consultant, Zeeva Fertility
MBBS – Bharati Vidyapeeth Deemed University, Pune • MS (Obstetrics & Gynaecology) – Bharati Vidyapeeth Deemed University, Pune • Fellowship in Reproductive Medicine – IIRFT, Delhi • Cosmetic Gynaecology – ILAMED, Delhi • Fellowship in Gynae Ultrasound – Randhawa Institute, Delhi
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7 years of experience

Dr. Ayushi Bhardwaj

IVF & Fertility Specialist
MBBS • MS (Obstetrics & Gynaecology) • DNB • FMAS • Fellowship-trained IVF Specialist
10+ Years Experience

Dr Deepika Mann

Associate - IVF Consultant
MBBS from K.S. Hegde Medical Academy, Mangalore • M.S from jjmmc, Davangere,karnataka • Fellowship in Reproductive Medicine from International Fertility Centre, Delhi
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Our cutting-edge fertility centres across Delhi NCR — Noida, Delhi, Ghaziabad and Greater Noida

Zeeva Fertility, Sector 63, Noida

H 1A, 37, H Block, Sector 63, Noida, Uttar Pradesh 201301

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10 am - 6 pm

Zeeva Fertility in South Extension, Delhi

3rd Floor, M-2, South Extension II, Block M, New Delhi, Delhi 110049

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Zeeva Clinic, HA 103A, First Floor, Sector 104, Noida, Uttar Pradesh 201304

(+91) 7669381393

11 am - 1 pm & 5 am - 9 pm

Greater Noida to Gaur City 1 Greater Noida West

Zeeva Fertility, 9th Floor, NH-3, GH 01, Gaur City 1, Sector 4, Greater Noida west, Ghaziabad, Uttar Pradesh 201009

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Zeeva Fertility in RDC, Ghaziabad

District Centre, RDC, Sector 15, Sector 10, Raj Nagar, Ghaziabad, Uttar Pradesh 201002

(+91) 7669381393

2 pm - 5 pm

Zeeva Fertility in Indirapuram, Ghaziabad

GF-01, 698, Niti Khand I, Indirapuram, Ghaziabad, Uttar Pradesh 201014

(+91) 7669381393

6 pm - 8 pm

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— Common questions

Fertility Questions, Answered

What Are The Success Rates Of IMSI?

The study shows that IMSI technology increased the success rate from 33% to 66%

Physiological ICSI method is successful and has a higher success rate of 60%. In some cases, it may also increase from 80% to 90%.

IMSI is recommended under the following circumstances:

  1. The male partner’s sperm counts are less
  2. The semen sample contains a higher level of abnormally shaped cells
  3. The previous outcomes have been negative

The sperm micromanipulation like ICSI is very useful for treating couples in which the male partner has a less or no sperm concentration or motility or both. Also, the study has shown that IMSI, using spermatozoa selected under high magnification mainly associated with more pregnancy rates in couples with repeated implantation failures.

Since it is possible to extract the healthiest, most motile and the potent sperm cells it gives the advantages in increasing the success rates of the fertilization process.

During IMSI (intracytoplasmic morphologically selected sperm injection) a sperm is tested by using a high-powered digital microscope. This microscope can enlarge the sperm image up to 6000-8000 times thereby allowing the fertility specialists to examine the sperm meticulously for any shape and size abnormalities and choose the best sperm for the fertilization process in ICSI IVF.